AestheFill – a new era of collagen biostimulants

Aesthefill is an injectable product that performs deep tissue regeneration to reduce the signs of facial aging. Aesthefill is made from Poly-D and L-lactic acid ( PDLLA) , which is a biocompatible and biodegradable material approved by the US Food and Drug Administration (FDA) and is also used in skin tightening threads. It naturally stimulates skin cells to produce their own collagen.

The preparation uses spherical particles of polylactic acid, called thermoplastic and biodegradable polylactide, which is obtained from corn or potato starch by polymerization. The biodegradation of the gel occurs independently: due to hydrolysis, polylactide gradually breaks down into lactic acid and glycogen, and is then naturally eliminated from the body.

As soon as the product enters the skin, it begins to actively fill the voids that arise due to skin aging and the loss of its own structural proteins. At the target site, polylactide molecules immediately start the process of tissue regeneration and collagen formation, which completely restores skin volume and smoothes even deep wrinkles. This is due to the special properties of AestheFill molecules, which, due to their porous structure, ensure the most effective collagenogenesis. Fibroblasts (skin cells) begin to function both outside and inside the microspheres.

In addition, polylactic acid actively stimulates the production of hyaluronic acid by mature skin cells. The uniqueness of the filler lies in the fact that after the breakdown and complete elimination of the main active ingredient from the body (this process takes an average of 3 to 4 months), the place where the gel was inserted is not left empty, but new collagen and elastin. Therefore, the effect will last for a long time - until the breakdown of your own collagen and elastin begins due to age factors. At that time, the procedure can be repeated. The polylactide contained in the AestheFill hydrogel has a porous structure with finely dispersed particles of the same size, so the gel is evenly distributed under the skin.

The main indications for the use of AestheFill hydrogel are as follows:
– lipodystrophy of the face, neck, décolleté and hands, which causes loss of skin volume, sagging, loss of elasticity and density;
– sunken areas of the face – sunken cheeks, cheekbones, sunken nose and tear trough;
– deep wrinkles (in the corners of the eyes, around the mouth, nasolabial and pre-chin wrinkles);
– atrophic and postoperative scars;
– irregularities in facial shapes and contours (asymmetry, reduction in volume).

The product is injected directly into the most problematic areas or applied to the entire face if the skin looks flabby, dehydrated and atonic. The procedure is completed with a light massage, during which the inner layers of the skin are evenly filled with the gel.

Aesthefill – fast and long-lasting results

The result becomes noticeable after the first procedure. Wrinkles are smoothed out, visible volume is created. True, a week after AestheFill injections, a slight decrease in volume is still possible (the solvent of the drug - water - will be removed from the treated area), but this will not affect the quality of the result.

Polylactic acid and AestheFill based on it are safe for the body. As mentioned, polylactic acid is naturally excreted from the body. This means that the patient should not fear health problems associated with the presence of non-degradable polymers in the body. The product does not migrate to adjacent tissues. All polylactic acid molecules introduced into the dermis remain in the desired layer and firmly maintain the volume in the injection area.

An additional advantage is the regular geometric shape of polylactic acid particles, which prevents clogging of small blood vessels. The advantages of AestheFill are also added by the fact that during the procedure the doctor can stop the desired concentration and perform work at different levels of the dermis (deep and superficial).

Discover Poly-D and L-lactic acid (PDLLA) benefits with AestheFill

The main ingredient of AestheFill preparations is PDLLA (poly-D, L-lactic acid). This is a unique combination of D- and L-lactide, which ensures a porous microsphere structure, uniform collagen production, rapid suspension preparation, uniform structure without lumps. Round PDLLA particles, due to their spherical shape, ensure optimal safety and reliability, confirmed by clinical studies and the FDA. AestheFill injections result in the formation of collagen fibers with strong covalent bonds. The spherical shape of the particles ensures a high percentage of fibroblasts for the formation of new collagen. The effect of AestheFill is skin tightening, replenishment of natural volume, restoration of contours lost with age. AestheFill is successfully used to treat scars, including post-acne.

In summary, AestheFill Poly-D and L-lactic acid ( PDLLA) dermal filler works in the deep dermis, gradually stimulating collagen production to correct wrinkles, skin irregularities and replace facial volume loss due to the aging process. AestheFill is used to temporarily correct sagging skin by injecting it into the subcutaneous layer of the facial skin. Unlike traditional dermal fillers, AestheFill more subtly replaces lost collagen over time and adds facial volume, giving you a more natural look. Do you want to surprise your clients with an innovation in the dermal filler market - effective AestheFill injectables? Contact your manager or write an email to info@mesoderma.eu!

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