As the human body ages, it changes, losing some of its flexibility. Joints are no exception. They wear out, and with age, the lubrication in the joints becomes thinner and less slippery. Over time, osteoarthritis can develop. What exactly is it and how can you deal with this health problem?
What is osteoarthritis?
Osteoarthritis is a typical wear and tear or thinning of the articular cartilage, most often in the knee. The wear and tear of the cartilage in the knee joint leads to inflammation of the joint capsule. Of course, this can also cause pain in younger patients, as age is not the only indicator. Other risk factors (obesity, congenital or acquired joint malalignment and overuse) can also lead to a deterioration in the condition of the joint.
Osteoarthritis treatment options
Various products can be used to successfully treat osteoarthritis, such as platelet-rich plasma (PRP) or hyaluronic acid (HA) injections. Cellular matrix is a unique medical device for the preparation of platelet-rich plasma (REGENPRP) in combination with hyaluronic acid. Hybrid osteoarthritis treatment with Cellular matrix benefits from the synergistic clinical effects of both products. The medical device is manufactured in Switzerland and is used in more than 60 countries worldwide.
It was developed by Regenlab®, a leading company in the production of medical products for the preparation of platelet-rich plasma. Regenlab provides expertly designed and patented medical devices for the preparation of platelet-rich plasma, CE certified and registered with most national agencies worldwide.
How does hybrid osteoarthritis therapy work with Cellular matrix®?
A small amount of blood is collected directly from a vein into a medical device through a specially designed closed system. Specific blood components are separated by centrifugation. A patented separating gel forms a physical barrier between the blood components. The body's regenerative elements, such as plasma and platelets, are separated from inflammatory blood elements. This process takes place in a closed system, resulting in a sterile product.
The patented REGENPRP and hyaluronic acid blend is directly injected by a physician, following standard aseptic guidelines and best practices for injecting the product into the knee joint. The full benefits of the Cellular Matrix procedure and the activation of regenerative biological processes may only be felt after a few weeks, but Cellular Matrix treatment provides long-term improvement in knee osteoarthritis symptoms.

What is REGENPRP®?
REGENPRP® is a patient platelet concentrate prepared using Regenlab medical devices. It is valuable because platelets play an important role in tissue repair mechanisms. They provide essential growth factors involved in the formation of new tissues. In addition, platelets also stimulate cells to produce new extracellular matrix and form new blood vessels. Plasma contains many factors necessary for cell survival, such as nutrients, vitamins, electrolytes, hormones, growth factors and proteins.
Hyaluronic acid optimizes the state of platelet-rich plasma to provide additional benefits to osteoarthritis patients. Both PRP and HA are widely used to improve joint lubrication, modulate inflammation, and alter the catabolic microenvironment of the joint, in order to not only reduce clinical symptoms but also slow the progression of osteoarthritis.
When PRP and HA are used together, this effect is enhanced and prolonged. HA creates a biologically active scaffold in which platelets gradually release growth factors. REGENPRP does not negatively affect the mechanical, elastic or viscous properties of HA. Cellular matrix is a unique, legally approved, patented technology that allows for the safe, closed-loop preparation of a cell-friendly PRP-HA network in which platelets and plasma components are retained. CM-PRP-HA has an excellent safety profile in clinical practice.
Tips to prevent further joint wear and tear to support your healing:
- Dietary changes to reduce weight.
- Avoid rapid twisting movements and painful bending positions.
- Regular joint-friendly exercise, such as walking, swimming, cycling, and dancing, can help.
In conclusion, hybrid therapy offers a way out of the vicious cycle of osteoarthritis. Cellular matrix® is a unique technology that combines two of the most promising natural treatments – PRP and HA.

